To the obese stomach malfunction you

According to an Australian study, the mechanism that has the stomach to detect how satisfied we are eating is damaged in obese individuals, although the good news is that it recovers once we lose weight and maintain it.

In particular, Stephen Kentish and his colleagues at the University of Adelaide have published a study in the International Journal of Obesity, which shows the nerves of the stomach responsible for identifying that it is full to lose sensitivity after consuming a diet high in fat in the long run.

To this is added that leptin, the hormone that normally sends to the brain the satiety signal, also works worse in people with a few pounds more. “These two combined mechanisms make the obese need to eat more to feel full, which becomes a snake that is death tail”, clarify the scientists.

The researchers say that this would be one of the reasons why the people who lose weight during a diet tend to recover it quickly. In fact it is estimated only 5% of those slimming maintain weight loss for at least two years, something that the new research could help remedy.

Do Black Pepper Fight Obesity?

PimientaEn effect. Korean Incheon Jong and So-Jong Um scientists discovered some time ago that the black pepper (Piper unigram) manages to reduce the levels of fat in the bloodstream. Now, in an article published in the Journal of Agricultural and Food Chemistry, the researchers explain the molecular basis of the effect of “grease” of this condiment, which attributed to the pipeline, the substance that gives it its characteristic (and spicy) flavor.

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Pipeline is an alkaloid that interferes with the activity of the genes that control the formation of new fat cells. Thus, operated a metabolic reaction in spine keeps the fat under control. The use of extracts of black pepper, suggest the authors, could help combat obesity and other related diseases.

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They discover the ‘fat gene’

The FTO gene had been appointed in earlier studies as ‘a gene for obesity’. Now, new research has identified another gene associated with this serious health problem that more than 60% of the Spanish population. The new gene, called IRX3, would be responsible for the increase in body fat.

The study, carried out by scientists from many universities in USA, Canada or Spain, concludes that this ‘fat gene’ is the real head of the reason why we are fat. To do this, they conducted an experiment with mice, mapping behavior of the promoters, the regions of DNA that activate gene expression within the FTO gene. Thus, the scientists found that the FTO gene not directly mingled with obesity, but another gene, the IRX3.

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In order to confirm this discovery, they performed another experiment to check the involvement of this new gene in weight gain. Thus, they observed developments and mice inoculated with this new gene in mice without the gene.

The result was that the mice with the gene IRX3 won almost twice the weight with a diet high in fats; the mice without the gene IRX3 not their growth although feed food waste and were even thinner than usual, with a reduction of between 25 and 30% of their body weight, due to loss of fat and an increase in metabolic rate.

The results of the study, which were published in the journal Nature, confirm that IRX3 gene is controlled the body mass, therefore indicating that genetic predisposition to obesity is given, in part, by our brain.

Being Obese 25 Can Lead To A Severe Obesity 35

Overweight at age 25 increases the risk of serious health problems in less than one decade. It is the conclusion of a recent study carried out by the universities of New York and Wyoming (USA) and published in the American Journal of Preventive Medicine.

The researcher’s analyzed data from the national study of health and nutrition of 1999-2010 USA (NHANES), with object relate to the (BMI) body mass index at age 25 with the risk of obesity 10 years view more and its effect on health.

Thus, they discovered that the men who were obese with 25 years had a probability of a 23.1% have obesity class III (IMC+40) after the age of 35. For women the percentage was much higher: a probability of a 46.9% have severe obesity with 35 years.

The positive side of the conclusions of the study linking obesity in their twenties as an indicator of cardiovascular risk and metabolic syndrome, is that the loss of weight at any stage of life can help reduce it. That is, regardless of the amount of time that someone has always had overweight, the loss will be a help to reduce the risk of health problems in the future.

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“The results suggest that the biological risks of obesity long term are mainly due to the probability of being obese adult and not at the time during which it has been obese. This is, to some extent, good news since it shows that young people with overweight and obesity can take steps to cease to be can prevent their biological risk factors”, says Jennifer B. Dowd, leader of study.

Digestive Bacteria In Thin People Can Use As Slimming

Receiving a handful of micro-organisms that live in the digestive system of thin people, obese individuals may lose weight. This follows the work of a group of scientists from the universities of Washington, Colorado and Stanford, all of them in the United States, which after implanting bacteria from the human intestine in mice have managed to alter its metabolism and speed up your metabolic rate, resulting in a loss of weight.

The researchers also showed that extracting fecal bacteria from the bowel movements of adult twins in which one of the Sisters was obese and another thin, and transplanting the germs in rodents, mice with microbes in obese individuals gained more weight than those who received bacteria from thin subjects.

“In other words, the weight gain can be transmitted human mice through their digestive microbes”, concludes Rob Knight, co-author of the study published by the journal Science and which could lead to a new remedy against overweight and obesity.

The content of the diet also influences the effect of this therapy. Specifically, in the experiment, the scientists observed that the colonization process did not take place when the animals are supplied a diet low in fiber and high in carbohydrates and fats.

Have You Completed The 50? Get Resistance Exercises

only older adults should exercise to avoid the loss of strength and muscle with aging, but that the “golden years” can be good to become stronger, according to a study conducted by the University of Michigan (USA), which recommended exercise of resistance from the 50, or even 40, “to increase the muscle tissue and the ability to operate more efficiently in daily life”.

Normally, sedentary adults over the age of 50 can expect a loss of muscle mass up to 180 grams per year. ? This only gets worse as people age. But even early in adulthood, in 30, 40, 50, one can begin to see a deterioration if not performing activities to acquire strength, “says Mark Peterson, a researcher from the Department of physical medicine and rehabilitation at the University of Michigan.? Our analysis shows that no matter the age the person is, because they can improve his strength significantly with progressive resistive exercise, even to the eighty and ninety years of age”, he says.

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Progressive resistance training means that the amount of weight used, the frequency and the duration of the training sessions are altered over time to accommodate the individual progress.

In an article published in The American Journal of medicine, Peterson and his colleagues shows that after an average of 18-20 weeks of training with progressive resistance, an adult can add more than 1,000 grams of muscles and increase their strength in general in a 25 to 30 percent.

Peterson concluded that all persons over the age of 50 years should be considered too seriously engage in resistance exercises. A good way to start a resistance training program, especially for relatively sedentary people – and after having a permit medical to make it – is to use your own body weight for several exercises.

The exercises that can be done using the weight of your body include squatting, lifting of hips, as well as non-traditional exercises that progress through a full range of movement, such as Yoga, Tai Chi and Pilates.

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After getting used to these activities, older adults can do a more advanced in a gym strength training. A professional trainer with experience with special groups can help in the transition. While resistance training progresses, weights and machines are introduced, Peterson recommended to incorporate full body exercises that use more than one joint and muscle groups simultaneously, such as exercises with leg, chest and rowing. These are more safe and effective in the development of muscle mass.